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in some embodiments, the serpina-1 polypeptide and or albumin polypeptide is measured using an immunological assay.

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to determine whether proteolytic pathways regulate differently serpina2 online and a1, stably transduced hela cells were treated with the proteasome inhibitor n-acetyl-l-leucyl-l-leucyl-l-norleucinal alln and with the autophagy inhibitor 3-methyladenine 3ma .

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hela cells were stably transduced with serpina2 v1, v2 and v3 and serpina1 m1, s and z vectors.

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while we were not able to identify the exact proteases that negatively impact membrane stability in md or with Purchase acute injury, serpina3n is known to block an array of serine proteases such as cathepsin g, granzyme b, elastase, trypsin, chymotrypsin and mmp9, as well as select cysteine proteases 8,13,15,35 .

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elevated expression and activity of serpina3n has been shown to promote wound healing in several injury models online including punctures in the skin, aortic aneurysm and neuron damage 10 13 .

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